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Harmful Protein-Coding Mutations in People arose Largely in the Past 5,000 to 10,000 Years

By Guest PostDecember 2, 2012Sciencea, africa migration, african, age, alzheimer, c, dating, discovery, dna code, dna sequence, Europe, european ancestry, evolutionary geneticist, future generation, g, gene, genetic variants, hardening, harmful, heart arteries, human, human diaspora, joshua akey, mesopotamia, metabolic pathways, middle east, model, mutation, nucleotide, out of africa, paralysis, premature ovarian failure, protein coding gene, protein coding mutation, seattle, single nucleotide, t, tap energy, university, variation, Washington, wenqing fu

A study dating the age of more than 1 million single-letter variations in the human DNA code reveals that most of these mutations are of recent origin, evolutionarily speaking. These kinds of mutations change one nucleotide – an A, C, T or G – in the DNA sequence. Over 86 percent of the harmful protein-coding mutations of this type arose in humans just during the past 5,000 to 10,000 years.

Some of the remaining mutations of this nature may have no effect on people, and a few might be beneficial, according to the project researchers. While each specific mutation is rare, the findings suggest that the human population acquired an abundance of these single-nucleotide genetic variants in a relatively short time. (more…)

Global Sea Level Likely to Rise as Much as 70 Feet in Future Generations

By Guest PostMarch 22, 2012Environmentandrew kulpecz, atmosphere, atmospheric temperature, core, degrees celsius, earth, east antarctic, eniwetok atoll, future generation, global warming, greenland, humankind, ice sheets, james browning, james wright, kenneth miller, michelle kominz, mountain glaciers, new zealand, pacific ocean, partial melting, richard lane, rise of sea level, rock, Rutgers University, sea level, sindia sosdian, virginia, west antarctic, yair rosenthal

*Scientists looked back in time–in the geologic record–to see the future*

Even if humankind manages to limit global warming to 2 degrees Celsius (3.6 degrees Fahrenheit)–as the Intergovernmental Panel on Climate Change recommends–future generations will likely have to deal with a completely different world.

One with sea levels 40 to 70 feet higher than at present, according to research results published this week in the journal Geology. (more…)

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Harmful Protein-Coding Mutations in People arose Largely in the Past 5,000 to 10,000 Years

Global Sea Level Likely to Rise as Much as 70 Feet in Future Generations