Tag Archives: hormone

Society Bloomed with Gentler Personalities, more Feminine Faces

DURHAM, N.C. – Modern humans appear in the fossil record about 200,000 years ago, but it was only about 50,000 years ago that making art and advanced tools became widespread.

A new study appearing Aug. 1 in the journal Current Anthropology finds that human skulls changed in ways that indicate a lowering of testosterone levels at around the same time that culture was blossoming. (more…)

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Elusive leptin

Researchers find first evidence of fat-regulating hormone in avian species

Since leptin was discovered 20 years ago, more than 115,000 papers have been published on this protein in humans, and another 5,000 have appeared on leptin in mice.

Leptin’s popularity is not surprising, as the hormone is the principal marker for the development of morbid obesity in humans. Leptin and its receptor play critical roles in the control of food intake and energy expenditure, thereby affecting body weight, abdominal fatness, thermogenesis, insulin sensitivity, and lipid metabolism. (more…)

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Vicious cycle: Changes in brain chemistry sustain obesity

In a new discovery reported in the Journal of Biological Chemistry, Brown University and Lifespan researchers show that in the brain cells of rats, obesity impedes the production of a hormone that curbs appetite and inspires calorie burning. The root cause appears to be a breakdown in the protein-processing mechanism of the cells. In the lab, the researchers showed they could fix the breakdown with drugs.

PROVIDENCE, R.I. [Brown University] — With obesity reaching epidemic levels in some parts of the world, scientists have only begun to understand why it is such a persistent condition. A study in the Journal of Biological Chemistry adds substantially to the story by reporting the discovery of a molecular chain of events in the brains of obese rats that undermined their ability to suppress appetite and to increase calorie burning. (more…)

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Injectable Nano-Network Controls Blood Sugar in Diabetics for Days at a Time

In a promising development for diabetes treatment, researchers have developed a network of nanoscale particles that can be injected into the body and release insulin when blood-sugar levels rise, maintaining normal blood sugar levels for more than a week in animal-based laboratory tests. The work was done by researchers at North Carolina State University, the University of North Carolina at Chapel Hill, the Massachusetts Institute of Technology and Children’s Hospital Boston.

“We’ve created a ‘smart’ system that is injected into the body and responds to changes in blood sugar by releasing insulin, effectively controlling blood-sugar levels,” says Dr. Zhen Gu, lead author of a paper describing the work and an assistant professor in the joint biomedical engineering program at NC State and UNC Chapel Hill. “We’ve tested the technology in mice, and one injection was able to maintain blood sugar levels in the normal range for up to 10 days.” (more…)

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Breastfeeding: Not only for young teens

When a teen mom is considering breastfeeding, it may be a tough task for her to break misconceptions, she has about breastfeeding. For example, many teens prefer bottle feeding as a healthier choice over breast feeding. They also believe that their breasts will lose their shape and it is “old school.” Teen moms, just like adults consider many factors when choosing breastfeeding.

Breastfeeding is by far one of the most natural attributes of the human body. Breastfeeding is a nature’s gift and has its own benefits:

· According to research, when teen moms breastfeed their baby immediately after delivery, the uterus slowly contracts reducing the risk of post-labor hemorrhage. Also, nursing helps you to slowly regain your per-pregnancy weight, which often results in shedding off those extra pounds. Breastfeeding when done the right way, slows periods, which acts as a effective form of birth control. This is really beneficial for teen moms who cannot access other forms of birth control during breastfeeding. Breastfeeding also reduces the chances of developing ovarian cancer and breast cancer. (more…)

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Scientists Reveal Quirky Feature of Lyme Disease Bacteria

Unlike most organisms, they don’t need iron, but they crave manganese

Scientists have confirmed that the pathogen that causes Lyme Disease—unlike any other known organism—can exist without iron, a metal that all other life needs to make proteins and enzymes. Instead of iron, the bacteria substitute manganese to make an essential enzyme, thus eluding immune system defenses that protect the body by starving pathogens of iron.

To cause disease, Borrelia burgdorferi requires unusually high levels of manganese, scientists at Johns Hopkins University (JHU), Woods Hole Oceanographic Institution (WHOI), and the University of Texas reported. Their study, published March 22, 2013, in The Journal of Biological Chemistry, may explain some mysteries about why Lyme Disease is slow-growing and hard to detect and treat. The findings also open the door to search for new therapies to thwart the bacterium by targeting manganese. (more…)

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Anxious Women’s Brains Work Harder

EAST LANSING, Mich. — In a discovery that could help in the identification and treatment of anxiety disorders, Michigan State University scientists say the brains of anxious women work much harder than those of men.

The finding stems from an experiment in which college students performed a relatively simple task while their brain activity was measured by an electrode cap. Only women who identified themselves as particularly anxious or big worriers recorded high brain activity when they made mistakes during the task.

Jason Moser, lead investigator on the project, said the findings may ultimately help mental health professionals determine which girls may be prone to anxiety problems such as obsessive compulsive disorder or generalized anxiety disorder. (more…)

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