Berkeley Lab scientists lead broadest survey yet of RNA activity in any animal
A consortium led by scientists from the U.S. Department of Energy’s Lawrence Berkeley National Laboratory (Berkeley Lab) has conducted the largest survey yet of how information encoded in an animal genome is processed in different organs, stages of development, and environmental conditions. Their findings paint a new picture of how genes function in the nervous system and in response to environmental stress. (more…)
UCLA life scientists have identified a gene previously implicated in Parkinson’s disease that can delay the onset of aging and extend the healthy life span of fruit flies. The research, they say, could have important implications for aging and disease in humans.
The gene, called parkin, serves at least two vital functions: It marks damaged proteins so that cells can discard them before they become toxic, and it is believed to play a key role in the removal of damaged mitochondria from cells. (more…)
When it comes to evolution, humans can learn a thing or two from primeval sea lampreys.
In the current issue of Nature Genetics, a team of scientists has presented an assembly of the sea lamprey genome – the first time the entire sequence has been decoded. The data is compelling as the sea lamprey is one of the few ancient, jawless species that has survived through the modern era.
The paper not only sheds light on how the venerable invasive species adapted and thrived, but it also provides many insights into the evolution of all vertebrates, species with backbones and spinal cords, which includes humans, said Weiming Li, Michigan State University fisheries and wildlife professor, who organized and coordinated the team. (more…)
In “before” and “after” photos from advertisements for wound-healing ointments, bandages and antibiotic creams, we see an injury transformed from an inflamed red gash to smooth and flawless skin.
What we don’t appreciate is the vital role that our own natural biomolecules play in the healing process, including their contribution to the growth of new cells and the development of new blood vessels that provide nutrients to those cells. (more…)
COLUMBUS, Ohio – A new way to visualize single-cell activity in living zebrafish embryos has allowed scientists to clarify how cells line up in the right place at the right time to receive signals about the next phase of their life.
Scientists developed the imaging tool in single living cells by fusing a protein defining the cells’ cyclical behavior to a yellow fluorescent protein that allows for visualization. Zebrafish embryos are already transparent, but with this closer microscopic look at the earliest stages of life, the researchers have answered two long-standing questions about how cells cooperate to form embryonic segments that later become muscle and vertebrae. (more…)
GAINESVILLE, Fla. — By analyzing the genes of bacteria, University of Florida researchers have moved a step closer to pinpointing how two brain disorders common in small-breed dogs occur.
The researchers found that the bacteria, known as Mycoplasma canis, invade dog’s cells and suppress their immune system responses. (more…)
Yale University researchers have discovered a key cellular mechanism that may help the brain control how much we eat, what we weigh, and how much energy we have.
The findings, published in the Feb. 28 issue of the Journal of Neuroscience, describe the regulation of a family of cells that project throughout the nervous system and originate in an area of the brain call the hypothalamus, which has been long known to control energy balances. (more…)
Smithsonian researchers report that the brains of tiny spiders are so large that they fill their body cavities and overflow into their legs. As part of ongoing research to understand how miniaturization affects brain size and behavior, researchers measured the central nervous systems of nine species of spiders, from rainforest giants to spiders smaller than the head of a pin. As the spiders get smaller, their brains get proportionally bigger, filling up more and more of their body cavities.
“The smaller the animal, the more it has to invest in its brain, which means even very tiny spiders are able to weave a web and perform other fairly complex behaviors,” said William Wcislo, staff scientist at the Smithsonian Tropical Research Institute in Panama. “We discovered that the central nervous systems of the smallest spiders fill up almost 80 percent of their total body cavity, including about 25 percent of their legs.” (more…)
