nervous system – Shamskm: A site to exchange knowledge and solutions

Early neural wiring for smell persists

By Guest PostMay 11, 2014Scienceagendas project, brown university, comparative policy, drexel university, energieversorger, gilad barnea, glomeruli, harald stadler, hedge fund, joshua borrajo, kommunale, lulu tsai, market swings, memory, nervous system, neural circuits, private, produce, psychiatric disorders, smell, tante ju

A new study in Science reveals that the fundamental wiring of the olfactory system in mice sets up shortly after birth and then remains stable but adaptable. The research highlights how important early development can be throughout life and provides insights that may be important in devising regenerative medical therapies in the nervous system.

PROVIDENCE, R.I. [Brown University] — To accommodate a lifetime of scents and aromas, mammals have hundreds of genes that each produce a different odorant receptor. The complex and diverse olfactory system they build remains adaptable, but a new study in the journal Science shows that the system’s flexibility, or plasticity, has its limits. Working in mice, Brown University scientists found that the fundamental neural wiring map between the nose and the brain becomes established in a critical period of early development and then regenerates the same map thereafter. (more…)

Vast Gene-Expression Map Yields Neurological and Environmental Stress Insights

By Guest PostApril 20, 2014Scienceberkeley lab, cadmium, environmental challenges, environmental stress, fruit fly, genome, geodynamo, heavy metals, hermann neumann, magnetic polarity, model organism, nervous system, neurological, peter driscoll, rna molecules, superchron, warmes bad

Berkeley Lab scientists lead broadest survey yet of RNA activity in any animal

A consortium led by scientists from the U.S. Department of Energy’s Lawrence Berkeley National Laboratory (Berkeley Lab) has conducted the largest survey yet of how information encoded in an animal genome is processed in different organs, stages of development, and environmental conditions. Their findings paint a new picture of how genes function in the nervous system and in response to environmental stress. (more…)

Boosting ‘cellular garbage disposal’ can delay the aging process, UCLA biologists report

By Guest PostJune 3, 2013Healthaging, aging research, alzheimer, anil rana, cardiovascular disease, cells, cellular garbage disposal, cellular machinery, david walker, diabetes, disease in humans, healthy life span, like symptoms, membrane structure, mitochondria, nervous system, neurodegenerative diseases, opposite effect, parkin gene, parkinsons disease, postdoctoral scholar, toxic, ucla biologists, vital functions

UCLA life scientists have identified a gene previously implicated in Parkinson’s disease that can delay the onset of aging and extend the healthy life span of fruit flies. The research, they say, could have important implications for aging and disease in humans.

The gene, called parkin, serves at least two vital functions: It marks damaged proteins so that cells can discard them before they become toxic, and it is believed to play a key role in the removal of damaged mitochondria from cells. (more…)

Ancient Lamprey DNA Decoded

By Guest PostMarch 6, 2013Environment, Natureadaptive immune system, ancient lamprey dna, backbones, brain, bygone eras, cambrian period, canadian government, chu yin yeh, chung davidson, data, decode, evolution, fossil records, great lakes, invasive species, jeramiah smith, kaben nanlohy, michigan state university, modern era, modern humans, multicelled creatures, nature genetics, nervous system, pathways, prehistoric species, salmon, scot libants, sea lamprey genome, single celled organisms, spinal cords, spine, titus brown, trout, US, vertebrates, weiming li, yu wen

When it comes to evolution, humans can learn a thing or two from primeval sea lampreys.

In the current issue of Nature Genetics, a team of scientists has presented an assembly of the sea lamprey genome – the first time the entire sequence has been decoded. The data is compelling as the sea lamprey is one of the few ancient, jawless species that has survived through the modern era.

The paper not only sheds light on how the venerable invasive species adapted and thrived, but it also provides many insights into the evolution of all vertebrates, species with backbones and spinal cords, which includes humans, said Weiming Li, Michigan State University fisheries and wildlife professor, who organized and coordinated the team. (more…)

UCLA Scientists Develop New Therapeutics that Could Accelerate Wound Healing

By Guest PostFebruary 27, 2013Healthaccelerate, acidic conditions, advertisement, antibiotic creams, bandages, basic, bfgf, bind heparin, biologist hugo armelin, bone regeneration, caitlin decker, chronic wounds, complex sugar, darice wong, dermatologist, diabetes, embryonic development, fibroblast growth factor, growth, growth factor, healing process, heather maynard, jenny kim, lloyd miller, motivation, natural biomolecules, naturally occurring, nervous system, new blood vessels, new cells, new therapeutics, nutrients, p sscopegma, pituitary gland, polymer, signaling molecule, stem cell renewal, structure of heparin, sung hye kim, thi nguyen, tissue regeneration, treat skin wounds, wound healing, wound healing ointments

In “before” and “after” photos from advertisements for wound-healing ointments, bandages and antibiotic creams, we see an injury transformed from an inflamed red gash to smooth and flawless skin.

What we don’t appreciate is the vital role that our own natural biomolecules play in the healing process, including their contribution to the growth of new cells and the development of new blood vessels that provide nutrients to those cells. (more…)

How Do Cells Tell Time? Scientists Develop Single-Cell Imaging to Watch the Cell Clock

By Guest PostNovember 18, 2012Science24 hour, activity, biological noise, cell, cell division, circadian clock, cyclic gene, cyclic protein, cyclical behavior, embryonic segmentation, embryonic segments, emilie delaune, gene, gene activation, life, lifespan, mesoderm, mitosis, molecular clock, muscle, nathan shih, nervous system, notch signaling pathway, oscillating pattern, oscillation, paul françois, phase, protein, sharon amacher, signal, signal reception, single cell, somites, synchronization, tissue segments, vasculature, vertebrae, visualization, visualize, zebrafish embryos

COLUMBUS, Ohio – A new way to visualize single-cell activity in living zebrafish embryos has allowed scientists to clarify how cells line up in the right place at the right time to receive signals about the next phase of their life.

Scientists developed the imaging tool in single living cells by fusing a protein defining the cells’ cyclical behavior to a yellow fluorescent protein that allows for visualization. Zebrafish embryos are already transparent, but with this closer microscopic look at the earliest stages of life, the researchers have answered two long-standing questions about how cells cooperate to form embryonic segments that later become muscle and vertebrae. (more…)

Analysis of Bacterial Genes May Help ID Cause of Dog Brain Disease, Say UF Researchers

By Guest PostOctober 2, 2012Health, Nature, Scienceanalysis, autoimmune, bacteria, balance, brain damage, brain disorder, brain inflammation, brain syndrome, brain tissue, cell, central, chihuahuas, christopher mariani, daniel brown, decreased alertness, dina michaels, disease, dog, florida, gene, genetic makeup, genital tract, gme, granulomatous meningoencephalomyelitis, immune system, karen vernau, macrophages, malteses, mycoplasma canis, necrotizing meningoencephalitis, nervous system, nme, pomeranians, pugs, renee barber, response, scott schatzberg, seizures, small breed, symptom, throat, university, viral agent, virus, yorkshire terriers

GAINESVILLE, Fla. — By analyzing the genes of bacteria, University of Florida researchers have moved a step closer to pinpointing how two brain disorders common in small-breed dogs occur.

The researchers found that the bacteria, known as Mycoplasma canis, invade dog’s cells and suppress their immune system responses. (more…)

Molecular Duo Dictate Weight and Energy Levels, Yale Researchers Find

By Guest PostFebruary 29, 2012Scienceanthony van den pol, bill hathaway, brain control, cells, cellular mechanism, energy, energy balance, hypothalamic neurons, hypothalamus, journal of neuroscience, mch, melanin concentrating hormone, nervous system, neurons, neurotransmitter, thyrotropin releasing hormone, trh, xiaobing zhang, yale university

Yale University researchers have discovered a key cellular mechanism that may help the brain control how much we eat, what we weigh, and how much energy we have.

The findings, published in the Feb. 28 issue of the Journal of Neuroscience, describe the regulation of a family of cells that project throughout the nervous system and originate in an area of the brain call the hypothalamus, which has been long known to control energy balances. (more…)

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