Tag Archives: shbg

Lifestyle, age linked to diabetes-related protein

A large, newly published study that includes more than 13,500 postmenopausal women has yielded the most definitive associations yet between certain lifestyle and demographic factors and levels of a promising early biomarker of type 2 diabetes risk.

PROVIDENCE, R.I. [Brown University] — Over the last decade researchers have amassed increasing evidence that relatively low levels of a protein called sex hormone binding globulin (SHBG) can indicate an elevated risk of type 2 diabetes and metabolic syndrome years in advance. (more…)

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Why Coffee Protects Against Diabetes

*Researchers discover molecular mechanism behind drink’s prophylactic effect*

Coffee, that morning elixir, may give us an early jump-start to the day, but numerous studies have shown that it also may be protective against type 2 diabetes. Yet no one has really understood why.

Now, researchers at UCLA have discovered a possible molecular mechanism behind coffee’s protective effect. A protein called sex hormone–binding globulin (SHBG) regulates the biological activity of the body’s sex hormones, testosterone and estrogen, which have long been thought to play a role in the development of type 2 diabetes. And coffee consumption, it turns out, increases plasma levels of SHBG.  (more…)

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